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KMID : 1101420180500020190
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Korean Journal of Clinical Laboratory Science
2018 Volume.50 No. 2 p.190 ~ p.196
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Relationship of the hs-CRP Levels with FBG, Fructosamine, and HbA1c in Non-diabetic Obesity Adults
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Oh Hye-Jong
Choi Cheol-Won
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Abstract
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Obesity has been reported to be a cluster of risk factors in the pathological ecology, In particular, there is increasing evidence that inflammation-related factors are associated with diabetes. This study examined the relationship between the hs-CRP level and FBG, fructosamine, and HbA1c in 4,734 non-diabetic adults aged 20 years or older, who were approved by the National Health and Nutrition Survey in 2015. The results showed that the FBG, fructosamine, and HbA1c levels increased with increasing BMI; the hs-CRP levels were the highest in the obese group, and HOMA-IR, an index of insulin resistance, was also significantly higher in the obese group. The hs-CRP level was the highest in obese adults. The levels of FBG, fructosamine. and HbA1c, which are involved in blood glucose control, increased with increasing hs-CRP level. The FBG, fructosamine, and HbA1c levels increased significantly with increasing hs-CRP level after adjusting for various related variables. These results suggest that the obesity-induced increase in hs-CRP is a risk factor for diabetes mellitus in non-diabetic adults. Therefore, proper dietary habits and regular exercise should prevent diabetes by preventing obesity in non-diabetic adults.
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KEYWORD
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FBG, fructosamine, HbA1c, hs-CRP, Obesity
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